Why is my weight loss so difficult — even with a perfect diet and perfect bloods ?
I remain committed to empowering you with clear scientific explanations. This topic however consistently ranks among the most challenging for my patients.
Over decades working in metabolic health and preventive care I hear a very common complaint;
“ Victoria, I’m eating right, exercising and following all the advice — why won’t the weight budge ?”
My GP tells me my bloods are all “normal”
Patients frustrated by fat that seems impossible to lose, energy that seems evasive, even with a seemingly perfect diet and consistent exercise.
Do you feel great after your 3rd morning coffee ? If so, this information is for you.
Why my Story is relevant and matters !
This was me in my early 40s.
Left hand picture, working hard, raising 3 beautiful daughters. Senior RN in Intensive care and Emergency and teaching at the College…. my days featured Advanced Life support and heavy critical care patient load accompanied by my own feelings of extreme fatigue, sore joints, skin rashes, gut upsets, moody but i pushed through …. and then came my shock diagnosis.
Right hand picture, 2 years later, well on the way with my healing journey of significant self discovery.
I’m sharing these so your understand that I have not always been of healthy weight and vital. Studying Nutrition was my FIRST BIG STEP. Understanding that being on the front line in Emergency and Intensive care, in combination with full on (incredible) motherhood was making me sick was my SECOND BIG STEP.
Everything and everybody was more important than me, I thought I was bullet proof. I SAVED lives.
I realised I had to change many things, not just to loose over 20% of my body weight but to survive a life threatening diagnosis and a pretty bleak outlook.
I wanted to enjoy my babies growing up.
My recovery was only possible by understanding, deeply, that the stresses in my life were making me sick.
And these stresses took many forms, some you may not have even considered.
This was one of the most powerful times in my life and so changed the whole trajectory of who I am as a person, both personally and professionally.
Please consider….
Stubborn weight gain accompanying unrelenting stress is common, especially when your HPA axis — your body’s central stress regulator is tired, or— is out of balance.
But stress wears many hats !!
you are not broken
you are not alone
you likely need to firstly understand this and start a realignment metabolically, an emphasis shift.
Let’s understand some science behind stress hormones as it can make all the difference.
The HPA axis connects important parts of your brain, the hypothalamus and pituitary gland with your adrenal glands.
This system regulates your body’s stress responses.
When you experience stress — emotional, psychological, inflammatory, food or even environmental — your HPA axis triggers the release of cortisol, your primary stress hormone.
Cortisol gets a bad wrap, but is not all bad
It helps you to ;
Maintain healthy blood sugar so you dont crash mid afternoon
Support your brain function and alertness
Have a healthy immune response
Calm inflammation
Regulate your blood pressure
The problem arises when stress is chronic and you don’t get BALANCE in your nervous system.
Continuous activation of your HPA axis interferes with your metabolism, your quality of sleep, appetite and fat storage — even if your diet is perfect.
Healthy Cortisol rhythm vs Chronic stress
In a healthy body,
Cortisol rises overnight and peaks in the morning to wake you up feeling bright, pain free and ready to embrace the day
Cortisol gradually declines throughout the day
Is lowest at night when you are yawning in the evening to allow for restful sleep (cortisol is related to melatonin with an important inverse relationship)
In chronic stressed states, Cortisol may be:
Elevated throughout the day
High at night
Blunted in the morning
Standard single Cortisol morning blood tests often miss these patterns.
At Gut Skin Clinic I often review multiple salivary cortisol testings to map the full 24-hour cortisol rhythm. This gives a more complete picture and can guide personalised weight loss strategies.
The diagram above explains the continuum of fat storage. Let’s look at some of the mechanisms.
Elevated Cortisol drives fat storage
Cortisol triggers gluconeogenesis in the liver, a process that stores glucose for times of famine or going without, problem is contemporary life is without famine resulting in increased blood glucose even without eating.
Higher blood sugar → higher insulin → fat storage.
Chronic stress leads to:
Insulin resistance
Central fat accumulation
Difficulty losing weight
Even with strict dieting, the body’s hormonal environment favours fat storage over fat burning.
2. Cortisol increases appetite & cravings
Stress hormones influence hunger signals and cravings.
There are multiple studies that demonstrate this in both animal and human models. High cortisol can make you:
Crave SWEET high-carb or salty foods
Eat more than usual often unconsciously
drink excess alcohol or other stimulants
This is biological, not a lack of willpower.
Elevated cortisol increases caloric intake and the tendency for emotional eating and fat storage in often the most stubborn places.
3. Cortisol slows metabolism by affecting Thyroid hormones
Cortisol can reduce conversion of T4 to T3 (the active thyroid hormone), this slows your metabolism and reducing fat burning.
Lower T3 =
Reduced mitochondrial activity
Lower basal metabolic rate
Less efficient fat metabolism
“High cortisol can make cells less responsive to existing T3 and can create symptoms of hypothyroidism even if blood tests appear “normal”.
4. Nighttime cortisol disrupts Sleep & autophagy
Human studies demonstrate that elevated evening cortisol impairs sleep, potentially worsens blood sugar control, and further disrupts appetite regulation.
Poor sleep creates a vicious cycle: stress → poor sleep → slower metabolism → more weight gain .
There are many studies illustrating this relationship as a strong risk factor for Type 2 mature onset Diabetes.
5. Low Cortisol can also be a factor
Some chronically stressed individuals eventually develop exhausted adrenal response where morning cortisol is very low :
Fatigue
Reliance on sugar or caffeine to kick start the day
Anxiety and low motivation
In these patients their weight gain may be driven by inflammation and metabolic dysfunction not simply high or low cortisol alone.
Does this sound familiar ? Maybe you feel great after your 3rd Morning coffee ?
Medically Supervised Weight Loss
At Gut Skin Clinic, I understand that stubborn weight gain is often not your fault. Your body is responding to stress and protecting itself.
My medical weight loss approach focuses on:
Baseline assessment of your metabolic health including a Body composition analysis, full history, food diary, knowledge of your daily habits and blood results review.
HPA axis clinical assessment and support
Blood sugar stability plan
Nutritional support personalised to you
Education
Sleep and circadian optimisation
Stress and emotional resilience strategies
in some cases, investigating tissue toxin burden.
a personalised supplement regime as requited
Addressing your root causes of hormone and cortisol driven weight gain can give many patients hope by tackling the issue in a different way, not simply to eat less and move more.
Patients often see better fat loss outcomes, improved energy, and reduced cravings — even if previous diets and exercise programs failed.
My message to you
If you feel like you’re “doing everything right” but the scale won’t budge, chronic stress and a hard drive that is out of balance may be sabotaging your efforts.
With personalised assessment and support, you can retrain your stress response and support a healthier metabolism…
I’ll help you re wire your “hard drive” to support a re calibration metabolically.
References
Epel, E. et al. (2000). Stress and body shape: stress-induced cortisol secretion is consistently greater among women with central fat. Psychosomatic Medicine, 62(5), 623–632.
Rosmond, R. (2005). Role of stress in the pathogenesis of the metabolic syndrome. Psychoneuroendocrinology, 30(1), 1–10.
Adam, T. C., & Epel, E. S. (2007). Stress, eating and the reward system. Physiology & Behavior, 91(4), 449–458.
Tsigos, C., & Chrousos, G. (2002). Hypothalamic–pituitary–adrenal axis, neuroendocrine factors and stress. Journal of Psychosomatic Research, 53(4), 865–871.
Spiegel, K. et al. (1999). Impact of sleep debt on metabolic and endocrine function. The Lancet, 354(9188), 1435–1439.
Heyma P et al (1982) Glucocorticolids decrease in conversion of Thyroxine into 3,5,3- tri-iodothyronine . Journal of Clinical science London. PMID 282948
Microbiome Gut and Regenerative Skin and Hair
in Neutral Bay, Cremorne, Mosman, Sydney.
Functional and Nutritional Medicine Practitioner (RN)
Microbiome Preferred Practitioner Microba labs.
Advanced Skin and Hair Regenerative Aesthetics
Compounded Skin Nutraceuticals
Professional Food and Nutritional Coach